Last time my 2 year old, Sophia was sick I gave her Tylenol because the dr. told me to do so but it wasn't helping her much. We had to go the Emergency room because she had a fever of 104. It scared me to death. They managed to get her fever under control and they told me that Motrin was more effective than Tylenol so I switched and within 2 to 3 days her cold had gone away and she was fine. This year she's been taking Motrin in the mornings.